Academic Appointment
Assistant Professor
Research Focus
Women's HealthOvarian DisordersEndometriosis CancersGenetics
Degrees / Designations

PhD

Mailing Address

2660 Oak Street
OVCARE, Robert HN Ho Research Centre
Vancouver BC V6H3Z6
Canada

Biography

Dr. Michael Anglesio is a principal investigator in the Ovarian Cancer Research Program and Women's Health Research Institute (WHRI) as well as an assistant professor in the Department of Obstetrics and Gynecology at the University of British Columbia. After studying microbiology and immunology at McGill University, he completed his PhD at the Pediatric Cancer Research Program and post-doctoral fellowship at the Peter MacCallum Cancer Center in Melbourne, Australia. His work focuses on further refining and differentiating ovarian cancer subtypes and the various origins of these subtypes. He has also taken a strong interest in understanding how malignancies arise from uterine tissues and is developing model systems to better understand how clear cell and endometrioid ovarian cancers differentiate as they arise from endometriosis.

 

Applicants:

Our research group is taking application for graduate students. Note that any accepted student will be accepted into an MSc stream and only pending appropriate performance and funding, may be offered the opportunity to progress to a PhD stream.

For position and projects in the lab please visit out lab website: https://www.EdgeResearch.ca

Application that are not relevant to our research group, and/or applicants that do not apply for advertised position, may not receive a reply. For graduate trainee applicants please keep in mind application deadlines are many months in advance of study start dates. 

For requirements and deadlines please visit program web sites for:

News and Awards

Honing in on precision treatments for endometriosis

Mar 14, 2023

Narrowing in on why endometriosis can lead to cancer

Mar 3, 2018

Publications

  • Clinical cancer research : an official journal of the American Association for Cancer Research -

    The Prognostic Effect of Immune Cell Infiltration Depends on Molecular Subtype in Endometrioid Ovarian Carcinomas.

    Heinze K, Cairns ES, Thornton S, Harris B, Milne K, Grube M, Meyer C, Karnezis AN, Fereday S, Garsed DW, Leung SCY, Chiu DS, Moubarak M, Harter P, Heitz F, McAlpine JN, DeFazio A, Bowtell DDL, Goode EL, Pike M, Ramus SJ, Pearce CL, Staebler A, Köbel M, Kommoss S, Talhouk A, Nelson BH, Anglesio MS
  • Cancer research -

    Cell State of Origin Impacts Development of Distinct Endometriosis-Related Ovarian Carcinoma Histotypes.

    Beddows I, Fan H, Heinze K, Johnson BK, Leonova A, Senz J, Djirackor S, Cho KR, Pearce CL, Huntsman DG, Anglesio MS, Shen H
  • Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie -

    A novel serous ovarian carcinoma model induced by DMBA: Results from OncoTherad® (MRB-CFI-1) immunotherapy preclinical testing.

    Ribeiro de Souza B, Oliveira G, Leme G, Brum Reis I, Augusto Tossini Cabral F, Lima Baggio de Paula J, Henrique da Silva Santos D, Ronca Felizzola C, Durán N, Anglesio M, José Fávaro W
  • The Journal of pathology -

    Validated biomarker assays confirm that ARID1A loss is confounded with MMR deficiency, CD8{{sup}}+{{/sup}} TIL infiltration, and provides no independent prognostic value in endometriosis-associated ovarian carcinomas.

    Heinze K, Nazeran TM, Lee S, Krämer P, Cairns ES, Chiu DS, Leung SC, Kang EY, Meagher NS, Kennedy CJ, Boros J, Kommoss F, Vollert HW, Heitz F, du Bois A, Harter P, Grube M, Kraemer B, Staebler A, Kommoss FK, Heublein S, Sinn HP, Singh N, Laslavic A, Elishaev E, Olawaiye A, Moysich K, Modugno F, Sharma R, Brand AH, Harnett PR, DeFazio A, Fortner RT, Lubinski J, Lener M, Tołoczko-Grabarek A, Cybulski C, Gronwald H, Gronwald J, Coulson P, El-Bahrawy MA, Jones ME, Schoemaker MJ, Swerdlow AJ, Gorringe KL, Campbell I, Cook L, Gayther SA, Carney ME, Shvetsov YB, Hernandez BY, Wilkens LR, Goodman MT, Mateoiu C, Linder A, Sundfeldt K, Kelemen LE, Gentry-Maharaj A, Widschwendter M, Menon U, Bolton KL, Alsop J, Shah M, Jimenez-Linan M, Pharoah PD, Brenton JD, Cushing-Haugen KL, Harris HR, Doherty JA, Gilks B, Ghatage P, Huntsman DG, Nelson GS, Tinker AV, Lee CH, Goode EL, Nelson BH, Ramus SJ, Kommoss S, Talhouk A, Köbel M, Anglesio MS
  • Human reproduction (Oxford, England) -

    Somatic PTEN and ARID1A loss and endometriosis disease burden: a longitudinal study.

    Tucker DR, Lee AF, Orr NL, Alotaibi FT, Noga HL, Williams C, Allaire C, Bedaiwy MA, Huntsman DG, Köbel M, Anglesio MS, Yong PJ
  • Clinical cancer research : an official journal of the American Association for Cancer Research -

    Endometrial Cancer Molecular Risk Stratification is Equally Prognostic for Endometrioid Ovarian Carcinoma.

    Krämer P, Talhouk A, Brett MA, Chiu DS, Cairns ES, Scheunhage DA, Hammond RFL, Farnell D, Nazeran TM, Grube M, Xia Z, Senz J, Leung S, Feil L, Pasternak J, Dixon K, Hartkopf A, Krämer B, Brucker S, Heitz F, du Bois A, Harter P, Kommoss FKF, Sinn HP, Heublein S, Kommoss F, Vollert HW, Manchanda R, de Kroon CD, Nijman HW, de Bruyn M, Thompson EF, Bashashati A, McAlpine JN, Singh N, Tinker AV, Staebler A, Bosse T, Kommoss S, Köbel M, Anglesio MS
  • The New England journal of medicine -

    Cancer-Associated Mutations in Endometriosis without Cancer.

    Anglesio MS, Papadopoulos N, Ayhan A, Nazeran TM, Noë M, Horlings HM, Lum A, Jones S, Senz J, Seckin T, Ho J, Wu RC, Lac V, Ogawa H, Tessier-Cloutier B, Alhassan R, Wang A, Wang Y, Cohen JD, Wong F, Hasanovic A, Orr N, Zhang M, Popoli M, McMahon W, Wood LD, Mattox A, Allaire C, Segars J, Williams C, Tomasetti C, Boyd N, Kinzler KW, Gilks CB, Diaz L, Wang TL, Vogelstein B, Yong PJ, Huntsman DG, Shih IM
  • Clinical cancer research : an official journal of the American Association for Cancer Research -

    Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE).

    Talhouk A, George J, Wang C, Budden T, Tan TZ, Chiu DS, Kommoss S, Leong HS, Chen S, Intermaggio MP, Gilks B, Nazeran TM, Volchek M, Elatre W, Bentley RC, Senz J, Lum A, Chow V, Sudderuddin H, Mackenzie R, Leong SCY, Liu G, Johnson D, Chen B, Group A, Alsop J, Banerjee SN, Behrens S, Bodelon C, Brand AH, Brinton L, Carney ME, Chiew YE, Cushing-Haugen KL, Cybulski C, Ennis D, Fereday S, Fortner RT, García-Donas J, Gentry-Maharaj A, Glasspool R, Goranova T, Greene CS, Haluska P, Harris HR, Hendley J, Hernandez BY, Herpel E, Jimenez-Linan M, Karpinskyj C, Kaufmann SH, Keeney GL, Kennedy CJ, Köbel M, Koziak JM, Larson MC, Lester J, Lewsley LA, Lissowska J, Lubiński J, Luk H, Macintyre G, Mahner S, McNeish IA, Menkiszak J, Nevins N, Osorio A, Oszurek O, Palacios J, Hinsley S, Pearce CL, Pike MC, Piskorz AM, Ray-Coquard I, Rhenius V, Rodriguez-Antona C, Sharma R, Sherman ME, De Silva D, Singh N, Sinn P, Slamon D, Song H, Steed H, Stronach EA, Thompson PJ, Tołoczko A, Trabert B, Traficante N, Tseng CC, Widschwendter M, Wilkens LR, Winham SJ, Winterhoff B, Beeghly-Fadiel A, Benitez J, Berchuck A, Brenton JD, Brown R, Chang-Claude J, Chenevix-Trench G, deFazio A, Fasching PA, García MJ, Gayther SA, Goodman MT, Gronwald J, Henderson MJ, Karlan BY, Kelemen LE, Menon U, Orsulic S, Pharoah PDP, Wentzensen N, Wu AH, Schildkraut JM, Rossing MA, Konecny GE, Huntsman DG, Huang RY, Goode EL, Ramus SJ, Doherty JA, Bowtell DD, Anglesio MS
  • Clinical obstetrics and gynecology -

    Endometriosis-associated Ovarian Cancers.

    Anglesio MS, Yong PJ
  • Histopathology -

    Identical TP53 mutations provide evidence that late-recurring tubo-ovarian high-grade serous carcinomas do not represent new peritoneal primaries.

    Anglesio MS, O'Neill CJ, Senz J, Gilks CB, McCluggage WG
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