The purpose of this study is to determine if the use of colchicine, a drug that reduces inflammation, can lower the risk of having a stroke or heart attack from blood clots compared to placebo, and improve recovery in people with a recent brain bleed.
The purpose of this study is to evaluate the efficacy of intermittent theta burst (iTBS) repetitive transcranial magnetic stimulation (rTMS) in improving depression symptoms over an accelerated treatment course of eight treatments per day for five days.
The purpose of this study is to test visual abilities and eye movements in patients with Parkinson's disease and healthy control participants and to link dysfunctions to cognitive abilities and disease severity.
The purpose of this study is to explore whether heart rate variability (HRV) normalization may serve as a surrogate marker of the changes in brain function caused by repetitive transcranial magnetic stimulation (rTMS) that are associated with symptomatic improvement in depression.
The purpose of this study is to obtain a realistic picture of the microbiological burden associated with catheter re-use, provide evidence for time spent on bladder management and provide evidence for time spent cleaning catheters for re-use.
The purpose of this study is to evaluate the effectiveness and tolerability of an oral study drug in individuals who experience upper limb essential tremor. Eligible participants will be randomly assigned to three different doses of the study drug or to a placebo.
The purpose of this study is to look at the link between regions of brain activity and impulsivity and to look at a non-invasive intervention called repetitive transcranial magnetic stimulation (rTMS) to help reduce the risk of impulsive behaviours.
The purpose of this study is to investigate whether Electrical Vestibular Stimulation (EVS) can lessen orthostatic hypotension in Parkinson’s disease patients. We aim to determine if individual precision-designed EVS stimulus can be optimized for improvements in hypotension.
The purpose of this study is to assess the efficacy of two drug treatments measured by annualized adjudicated relapse rate (ARR) in participants with relapsing forms of MS.
The purpose of this study is to investigate the impact of genetic and non-genetic risk factors for Alzheimer’s disease (AD), evaluate differential
effects of sex on AD risk, and predict diagnosis of AD using dementia risk scores derived from genetic and nongenetic risk factors.
The purpose of this study is to evaluate the feasibility of using repetitive transcranial magnetic stimulation (rTMS) to treat depression.
The purpose of this study is to test the safety and efficacy of TAK-079, a medicine to help people with generalized myasthenia gravis.
The purpose of this study is to is to examine the effects of 12 weeks of high-intensity interval training on the cognitive health of perimenopausal women.
The purpose of this study is to test the feasibility of magnetic seizure therapy for treating depression in patients diagnosed with Parkinson's Disease.
The purpose of this study is to evaluate the efficacy and safety of ocrelizumab ( Ocrevus®) compared with placebo in participants with primary progressive multiple sclerosis (PPMS).
The purpose of this study is examine the use of low concentration capsaicin (the active ingredient in chili peppers) cream applied for extended periods of time to help manage neuropathic pain after spinal cord injury.
The purpose of this study is to evaluate the safety and effectiveness of non-invasive electrical spinal stimulation for restoration of upper extremity function.
The purpose of this study is to determine whether a regular program of exercise, performed in a person's home or in fitness facility, can significantly reduce chronic pain in adults with spinal cord injury.
The purpose of this study is to determine ways to meet the social needs related to loneliness and isolation in seniors with dementia while examing barriers and successes surrounding the use of a robot-assisted, virtual care solution within care settings.
This project is investigating the immediate and long-term effects of non-invasive transcutaneous spinal cord stimulation (TCSCS) on bladder, bowel, and sexual function in people with SCI.